Multidisciplinární přístup v léčbě gliomů - astrocytomy a oligodendrogliomy

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Title in English Multidisciplinary approach in the treatment of gliomas - astrocytomas and oligodendrogliomas.
Authors

KAZDA Tomáš LAKOMÝ Radek POPRACH Alexandr HENDRYCH Michal KNIGHT Andrea ŠLAMPA Pavel

Year of publication 2020
Type Article in Periodical
Magazine / Source Postgraduální medicína
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.mf.cz/produkty/postgradualni-medicina/archiv/2020-2
Keywords gliomy; radioterapie; chemoterapie; prognostické faktory
Description Gliomas are one of the most common primary brain tumours. Despite of great progress in all medical disciplines, the prognosis of patients with this disease has not improved significantly in the last 15 years. The treatment strategy still relies on maximum safe tumour resection, radiotherapy and chemotherapy temozolomide (Stupp regimen). The decisionmaking process must take into account not only the known clinical and laboratory prognostic and predictive factors, but also the patient‘s preferences. Given the complexity of the issue, in which more than one discipline is involved, close multidisciplinary cooperation is required. Neither targeted therapy nor immunotherapy with checkpoint inhibitors have found much use. However, intensive research is still ongoing. The aim of this educational review is to summarize the current guidelines in the treatment of gliomas.
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