NAChRDB: Database of structural-functional annotations of nicotinic acetylcholine receptors

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Authors

CHARESHNEU Aliaksei PANT Purbaj RAMOS Ravi José Tristao SEHNAL David GÖKBEL Tugrul IONESCU Crina-Maria KOČA Jaroslav

Year of publication 2018
MU Faculty or unit

Central European Institute of Technology

Citation
Description Web-accessible database of residue-level structural-functional annotations of nicotinic acetylcholine receptors. NAChRDB is particularly useful for identifying gaps in knowledge and for guiding discovery through structural and molecular biology experiments, especially when exploring the allosteric mechanisms underlying neuromuscular nAChR function and pathology. NAChRDB contains annotations from published and unpublished studies. The relationship between publication and validation is central to the mission of NAChRDB, which is not to grant credibility to the reports, but rather to create the perfect venue for assessing the credibility of reports in the proper context of the knowledge accumulated so far.
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