大腸癌の診断方法

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Title in English How to diagnose colorectal cancer
Authors

SLABÝ Ondřej VYCHYTILOVÁ Petra SVOBODA Marek ŠACHLOVÁ Milana

Year of publication 2021
Type Patent
MU Faculty or unit

Central European Institute of Technology

Publisher
Patent's number JP6989863B2
Web Espacenet
Description The present invention relates to a method for diagnosing colorectal cancer and a method for predicting prognosis. In this method, piRNA-hsa-5937 (sequence: TCCCTGGTGGTCTAGTGGTTAGGATTCGGCA (SEQ ID NO: 1)), miR-23a-3p (sequence: AUCACAUUGCCAGGGAUUUCC (SEQ ID NO: 3)), miR-27a-3p (sequence: UUCACAGUGGCUAAGUUCCGC (SEQ ID NO: 4)). )) And one or more miRNAs selected from miR-142-5p (SEQ ID NO: CAUAAAGUAGAAAGCACUACU (SEQ ID NO: 5)) are used as biomarkers. The resulting method uses body fluid as input. Therefore, this method is non-invasive, has high sensitivity and specificity even in the earliest stages of the disease, and is cost-effective.
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