大腸癌の診断方法

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Title in English	How to diagnose colorectal cancer
Authors	SLABÝ Ondřej VYCHYTILOVÁ Petra SVOBODA Marek ŠACHLOVÁ Milana
Year of publication	2021
Type	Patent
MU Faculty or unit	Central European Institute of Technology
Publisher
Patent's number	JP6989863B2
web	Espacenet
Description	The present invention relates to a method for diagnosing colorectal cancer and a method for predicting prognosis. In this method, piRNA-hsa-5937 (sequence: TCCCTGGTGGTCTAGTGGTTAGGATTCGGCA (SEQ ID NO: 1)), miR-23a-3p (sequence: AUCACAUUGCCAGGGAUUUCC (SEQ ID NO: 3)), miR-27a-3p (sequence: UUCACAGUGGCUAAGUUCCGC (SEQ ID NO: 4)). )) And one or more miRNAs selected from miR-142-5p (SEQ ID NO: CAUAAAGUAGAAAGCACUACU (SEQ ID NO: 5)) are used as biomarkers. The resulting method uses body fluid as input. Therefore, this method is non-invasive, has high sensitivity and specificity even in the earliest stages of the disease, and is cost-effective.
Related projects:	Vytvoření diagnostické sady cirkulujících mikroRNA pro neinvazivní časnou diagnostiku a sledování pacientů s kolorektálním karcinomem