Metal Oxide Laser Ionization Mass Spectrometry Imaging of Fatty Acids and Their Double Bond Positional Isomers

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Authors	KOKTAVÁ Monika VALÁŠEK Jan BEZDEKOVÁ Dominika PRYSIAZHNYI Vadym ADAMOVÁ Barbora BENEŠ Petr NAVRÁTILOVÁ Jarmila HENDRYCH Michal VLČEK Petr PREISLER Jan BEDNAŘÍK Antonín
Year of publication	2022
Type	Article in Periodical
Magazine / Source	Analytical Chemistry
MU Faculty or unit	Faculty of Science
Citation
Web	https://pubs.acs.org/doi/10.1021/acs.analchem.2c00551
Doi	http://dx.doi.org/10.1021/acs.analchem.2c00551
Keywords	ozone; fatty acids; metal oxide; metal oxide laser ionization; MOLI MS; mass spectrometry imaging; MSI; double bond position; lipid isomers
Description	The article presents a novel combination of metal oxide laser ionization mass spectrometry imaging (MOLI MSI) technique with off-line lipid derivatization by ozone for the detection of fatty acids (FA) and their carbon-carbon double bond (C=C) positional isomers in biological tissues.
Related projects:	MALDI MS zobrazování izomerů lipidů lišících se pozicí dvojné vazby uhlík-uhlík Czech Infrastructure for Integrative Structural Biology