Cardiovascular Diseases
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| Year of publication | 2023 |
| Type | Chapter of a book |
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| Description | Cardiovascular diseases (CVDs) are the principal cause of death globally contributing to more than half of the mortality in Europe (42% on males and 51% on females) (Gillespie et al., 2013, Mozaffarian et al., 2015). There is growing interest in studying etiology, hallmarks, progress, and improved therapies for CVDs. Genetic background and cellular phenotypes are frequent morbidity and mortality causes (Aistrup et al., 2009, Stienen, 2015, van der Velden and Stienen, 2019), but those are not readily accessible for diagnostics. Stem-cell-derived cardiomyocytes (CMs) thus stands for readily available and ethically uncompromised model for basic research. |
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