Substituted aminothiazoles as inhibitors of nucleases

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Authors	PARUCH Kamil CARBAIN Benoit Jean-Pierre HAVEL Štěpán DAMBORSKÝ Jiří BREZOVSKÝ Jan DANIEL Lukáš SISÁKOVÁ Alexandra NIKULENKOV Fedor KREJČÍ Lumír
Year of publication	2023
Type	Patent
MU Faculty or unit	Faculty of Science
Publisher	United States Patent and Trademark Office
State	United States of America
Patent's number	US11584742
Web	https://worldwide.espacenet.com/patent/search/family/062017184/publication/US11584742B2?q=pn%3DUS11584742B2
Description	Compounds represented by the structural formula (1) R1, R2, R3, R4, R5, R6 are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.
Related projects:	Preclinical Progression of New Organic Compounds with Targeted Biological Activity CZ-OPENSCREEN: National Infrastructure for Chemical Biology