Kineticky a termodynamicky kontrolovaný průběh domino reakce - Syntéza nových 1,3-oxathiolů a 1,3-thiazolů

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Title in English Kinetically and Thermodynamically Controlled Domino-reaction - Synthesis of Novel 1,3-Oxathioles and 1,3-Thiazoles
Authors

PAZDERA Pavel FATHALLA Walid

Year of publication 2002
Type Article in Periodical
Magazine / Source Chemické Listy
MU Faculty or unit

Faculty of Science

Citation
Field Organic chemistry
Keywords Domino-reaction; Cascade-reaction; Quinazoline; Oxathiole; Thiazole
Description New two-component domino reaction of 1,1-disubstituted-3-(2-phenyl-3H-quinazolin-4-yliden)thioureas with phenacylbromides giving quinazolin-4-yl-1,3-thiazoles as kinetically controlled and quinazolin-4-yl-1,3-oxathioles as thermodynamically controlled products is described.
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