Haplotype analysis of the NADPH oxidase p22phox gene in patients with bronchial asthma

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie KAŇKOVÁ Kateřina ZNOJIL Vladimír
Year of publication	2009
Type	Article in Periodical
Magazine / Source	Int Arch Allergy Immunol
MU Faculty or unit	Faculty of Medicine
Citation
Field	Immunology
Keywords	NADPH oxidase; p22phox; asthma; polymorphism; haplotype; gene
Description	We sought to elucidate the role of genetic variability in the gene encoding p22phox subunit of the NADPH oxidase (CYBA, 16q24.3) in asthma susceptibility by means of association study of haplotypes based on three common single nucleotide polymorphisms (SNPs) -930A/G, 242C/T (H72Y) and 640A/G.
Related projects:	Genetické determinanty pro-/antioxidační rovnováhy v patogeneze respiračních nemocí