Haplotype analysis of the NADPH oxidase p22phox gene in patients with bronchial asthma

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Authors

IZAKOVIČOVÁ HOLLÁ Lydie KAŇKOVÁ Kateřina ZNOJIL Vladimír

Year of publication 2009
Type Article in Periodical
Magazine / Source Int Arch Allergy Immunol
MU Faculty or unit

Faculty of Medicine

Citation
Field Immunology
Keywords NADPH oxidase; p22phox; asthma; polymorphism; haplotype; gene
Description We sought to elucidate the role of genetic variability in the gene encoding p22phox subunit of the NADPH oxidase (CYBA, 16q24.3) in asthma susceptibility by means of association study of haplotypes based on three common single nucleotide polymorphisms (SNPs) -930A/G, 242C/T (H72Y) and 640A/G.
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