Septický šok při fatálně probíhající stafylokokové pneumonii: význam Pantonova-Valentinova leukocidinu - kazuistika

• Title in English: Septic shock in fatal pneumonia caused by Staphylococcus aureus: The significance of producing Pantone-Valentine leukocidine - case report
• Authors: BENEŠ Jiří; MYSLIVEC Ondřej; LAŠTÍKOVÁ Jarmila; GABRIELOVÁ Alice; PETRÁŠ Petr; PANTŮČEK Roman
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: Anesteziologie a intenzivní medicína
• MU Faculty or unit: Faculty of Science
• Web: http://www.prolekare.cz/anesteziologie-intenzivni-medicina-clanek?id=33475
• Field: Microbiology, virology
• Keywords: sepsis; pneumonia; Staphylococcus aureus; Panton-Valentine leukocidin
• Description: Necrotizing pneumonia caused by Staphylococcus aureus producing Pantone-Valentine leukocidin (PVL) is a rare but life-threatening disease. Early diagnosis of staphylococcal etiology is necessary for successful treatment. Linezolid is the first choice antibiotic that should be preferred to beta-lactams and vancomycin in this indication. We report a case of 29 year old man who was admitted for severe septic shock and incipient pneumonia and died 8 hours after admission despite intensive care. Staphylococcus aureus izolated from blood cultures produced PVL.

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