Flow Cytometry in Monoclonal Gammopathies

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Authors

KOVÁŘOVÁ Lucie VARMUŽOVÁ Tamara ZARBOCHOVÁ Pavla SUSKÁ Renata MUTHU RAJA K. R. ŠTOSSOVÁ Jana PENKA Miroslav HÁJEK Roman

Year of publication 2011
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords multiple myeloma;– monoclonal gammopathy; flow cytometry; plasma cell
Description The technological development of flow cytometry (FC) together with new findings reveal the need for immunophenotyping in research of monoclonal gammopathy (MG) because of its diagnostic, prognostic and predictive significance. The aim of the European Myeloma Network (EMN) is to standardize this analytical method and implement it into routine clinical examination. Since the overall significance and application of FC are still analysed, standardisation could help obtain more clinical relevant information in terms of MG pathophysiology.
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