Nucleosome DNA sequence structure of isochores

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Authors

FRENKEL Zakharia M. BETTECKEN Thomas TRIFONOV Eduard

Year of publication 2011
Type Article in Periodical
Magazine / Source BMC Genomics
MU Faculty or unit

Central European Institute of Technology

Citation
Doi http://dx.doi.org/10.1186/1471-2164-12-203
Field Genetics and molecular biology
Keywords NUCLEOTIDE-SEQUENCE; CHROMATIN DNA; SPLICE SITES; PATTERN; ELEGANS; GENOME
Description Significant differences in G+C content between different isochore types suggest that the nucleosome positioning patterns in DNA of the isochores should be different as well. Nucleosome positioning pattern as revealed by Shannon N-gram extension is strongly dependent on G+C content and different in different isochores. Species-specificity of the pattern is subtle. It is reflected in the choice of preferentially periodical dinucleotides.
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