Serotonergní receptory 5-HT3 hrají roli při expresi behaviorální senzitizace k účinkům metamfetaminu

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Title in English	Serotonergic 5-HT3 receptors play role in expression of behavioural sensitization to methamphetamine
Authors	PISTOVČÁKOVÁ Jana AMCHOVÁ Petra ŠULCOVÁ Alexandra
Year of publication	2012
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Development of sensitization to methamphetamine was shown after its repeated administration. 5-HT3 antagonist ondansetron blocked the development of behavioural sensitization to methamphetamine, while the co-administration of mCPB, the 5-HT3 receptor agonist, prevented the effect of ondansetron on the development of behavioural sensitization.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.