Occurrence of quaternary benzo[c]phenanthridine alkaloids in Stylophorum lasiocarpum (Oliv.) fedde

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Authors	PĚNČÍKOVÁ Kristýna URBANOVÁ Jana TÁBORSKÁ Eva
Year of publication	2012
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Attached files	konferencni_prispevky_Olomouc.pdf
Description	For a long time, quaternary benzo[c]phenanthridine alkaloids (QBAs) are known to exhibit diverse biological effects. A great deal of attention is devoted to the main alkaloids sanguinarine (SA ) and chelerythrine (CHE) and their cytotoxicity and induction of apoptosis. These alkaloids also display important anti-proliferative activities against cancer cell lines and have been discussed as potential cytostatic drugs for cancer treatment. In the last years also the other QBAs have received increased attention and new information regarding their biological activities has been published.
Related projects:	Příspěvek chemických a biochemických metodik ke studiu molekulární podstaty vybraných patologických stavů a onemocnění Benzofenathridinové alkaloidy-studium účinků na celulární a molekulární úrovni