Project information
NCMG: The National Centre for Medical Genomic
(NCMG)
- Project Identification
- LM2023067
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Cooperating Organization
-
Charles University
- Responsible person prof. Ing. Stanislav Kmoch, CSc.
University Hospital Brno-Bohunice
The National Centre for Medical Genomics (NCMG) is distributed, fully operating infrastructure of five
Czech laboratories developing and performing research in genomic medicine. Their activities include
implementation and adaptation of novel genomic technologies including generation, analysis,
archiving, sharing and displaying sequence data. Other activities are aimed at the exploration of issues
related to the genetic architecture of various diseases, implementation of genomic technologies into
routine diagnostics, and ethical aspects of genomic research and diagnostics.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 17
2024
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CF Day 2023
Year: 2024, type: Popularization text
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Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome
NPJ PRECISION ONCOLOGY, year: 2024, volume: 8, edition: 1, DOI
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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug
Leukemia, year: 2024, DOI
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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single-cell RNA sequencing
Molecular oncology, year: 2024, DOI
2023
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Analysis of chimeric reads characterises the diverse targetome of AGO2-mediated regulation
Scientific Reports, year: 2023, volume: 13, edition: 1, DOI
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Application of long-read sequencing in chronic lymphocytic leukemia cases with complex karyotype.
Year: 2023, type: Conference abstract
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Business Research Forum 2023
Year: 2023, type: Popularization text
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Desmocollin-1 is associated with pro-metastatic phenotype of luminal A breast cancer cells and is modulated by parthenolide
Cellular & Molecular Biology Letters, year: 2023, volume: 28, edition: 1, DOI
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EGFR stimulation enables IL-6 trans-signalling via iRhom2-dependent ADAM17 activation in mammary epithelial cells
Biochimica et biophysica acta : Molecular Cell Research, year: 2023, volume: 1870, edition: 7, DOI
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Enhanced in vitro culture of leukemic cells: Insights from collagen scaffolds and carboxymethyl cellulose-polyethylene glycol gel.
Year: 2023, type: Conference abstract