Vztah tloušťky nervových vláken sítnice a funkční citlivosti sítnice při vyšetření na oct a statickém perimetru
| Title in English | The relationship between retinal nerve fibers thickness and retinal functional sensitivity during oct and static perimeter examinations |
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| Authors | |
| Year of publication | 2024 |
| Type | Article in Periodical |
| Magazine / Source | Česká a slovenská oftalmologie |
| MU Faculty or unit | |
| Citation | |
| Web | zdroj |
| Keywords | RNFL, OCT, FDT perimeter, SE, macula, papilla. |
| Description | Aims: To demonstrate the dependence of the size of the thickness of the layer of nerve fibers on the retina and the functional sensitivity of the retina in healthy young individuals. We also secondarily investigated the relationship between refractive error and mean retinal thickness in the macula in healthy young subjects. Material and methods: The basic set contained 30 subjects with an average age of 23.4 ± 4.2 years. There was 1 man and 29 women in the congregation. These were young, generally healthy individuals without serious eye pathologies. The average value of the spherical equivalent in both eyes of all individuals was -1.2 ±2.5 D. We measured the thickness of the layer of nerve fibers in the papilla area (RNFL) and the average thickness of the retina in the area of the macula on a device OPKO Spectral OCT SLO Combination Imaging System (Opko Health, US). We performed a functional examination of the retina in the area up to 30° using a perimeter with a stimulus with a doubled brightness frequency (FDT) from the company Humphrey (Carl Zeiss). As a significant variable for comparison, we determined the mean retinal sensitivity deviation (MD) value. Due to the dependence of the measurements between the right and left eyes, we divided the file into two subsets (OD and OS), evaluated the interdependence of the variables separately for the right, and left eyes. Results: In our study, we did not demonstrate a statistically significant relationship between the average thickness of the retinal nerve fiber layer (RNFL) and the average value of retinal functional sensitivity (r = 0.18, p = 0.34) in the right eyes as well as in the left eyes of the examined subjects (r = 0.20, p = 0.29). We also did not find a statistically significant relationship secondarily between the variable called the spherical equivalent of the refractive error (SE) and the average thickness of the retina in the macula in the right eyes (r = 0.34, p = 0.06) and left eyes (r = 0.18, p = 0.32). Conclusion: When comparing the average size of the thickness of the nerve fibers in the papilla with the help of OCT examination and the functional sensitivity of the retina measured on the FDT perimeter, we did not find a statistically significant dependence in the group of right eyes or in the group of left eyes. We also achieved a similar result when examining the interdependence of the variables spherical equivalent of the refractive error of the eye and the average thickness of the retina in the macula. No statistically significant dependences were found for the group of right and left eyes. |
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