High-affinity lectins from pathogens: the potential targets for antiadhesive drug design

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Authors

ŠULÁK Ondřej MALINOVSKÁ Lenka CIOCI Gianluca HOUSER Josef KOSTLÁNOVÁ Nikola LAMEIGNERE Emilie POKORNÁ Martina IMBERTY Anne WIMMEROVÁ Michaela

Year of publication 2010
Type Article in Periodical
Magazine / Source Materials Structure in Chemistry, Biology, Physics and Technology
MU Faculty or unit

Faculty of Science

Citation
Field Biochemistry
Keywords lectin; antiadhesive therapy
Description Protein-carbohydrate interactions play an important role in many biologically relevant processes. The contribution is focused on lectins from human opportunistic pathogens, which display sub-micromolar range affinity towards their carbohydrate ligands.
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