Project information
Application of computer image analysis in optical microscopy
- Project Identification
- MSM 143300002
- Project Period
- 1/1999 - 12/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Informatics
- Keywords
- image analysis; image processing; segmentation; preprocessing; deconvolution; 3D analysis; 3D reconstruction; mathematical morphology; parallel computing; parallel algorithms; optical microscopy; confocal microscopy; automation; automated microscopy
Aim: The aim of the project is the research in the field of computer analysis of microscopic images, in the field of automation of the acquisition process and on-line image analysis and application of gained knowledge in praxis. The proposal assumes both continuation of running research of cell nucleus structure with clinical applications in diagnostics and prevention of leukemias and other cancer diseases as well as extension of the research into other application areas of computer analysis of microscopic images, biomedical as well as industrial. Content: Especially the algorithms of image preprocessing and segmentation will be studied with emphasis on deconvolution of 3D images, mathematical morphology operations and 3D image reconstruction from a series of 2D image slices. An intensive research will be led also in the area of parallel image analysis algorithms and parallelization of selected algorithms on multi-processor workstations using the equipment of Supercomputing centre MU.
Results
The aim of the project is the research in the field of computer analysis of microscopic images, in the field of automation of the acquisition process and on-line image analysis and application of gained knowledge in praxis.
Publications
Total number of publications: 88
2002
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Algorithms and data representation in the FISH 3.0 image processing system
Biophysics of the genome and its interactions, year: 2002
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Automated micro axial tomography of cell nuclei after specific labelling by fluorescence in situ hybridisation
Micron, year: 2002, volume: 33, edition: 7
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Automated multi-view 3D image acquisition in human genome research
3D data processing, visualization and transmission, year: 2002
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Biophysics of the Genome and Its Interactions
Year: 2002, type:
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Cell Nuclei Segmentation Using Star-Shaped Simplex Meshes
Biophysics of the Genome and Its Interactions, year: 2002
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Cytogenetics of Retinoblastoma
Biophysics of the genome and its interactions, year: 2002
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Development of software for automated micro-axialtomography
Biophysics of the genome and its interactions, year: 2002
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Effectivity of Spherical Object Reconstruction Using Star-Shaped Simplex Meshes
1st International Symposium on 3D Data Processing Visualization and Transmission, year: 2002
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FISH 3.0 client-server system for 3D optical microscope data storage and analysis
Biophysics of the genome and its interactions, year: 2002
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High-resolution cytometry network project: Towards remote and distributed acquisition, processing and visualisation of 3D image data in human genome research
3D data processing, visualization and transmission, year: 2002